Both teams are chasing a place in the top four in the English Premier League with just three games to go.
Chelsea are still in the hunt for glory in Europe as they are in the semi-finals of the Europa League and will qualify for the Champions League if they win it.
However, the same cannot be same of Manchester United who must win the tie against the Blues to keep hopes of a Champions League berth alive.
They have lost their last four games, and most recently, were beaten 0-2 by Manchester City in a domestic league tie.
What Time Is Man United Vs Chelsea Match?
The clash will take place at the Old Trafford on Sunday at 4:30 pm, Nigerian time and can be watched live on Supersports 3 on DSTV.
Man United Vs Chelsea Lineup
Here is the lineup for the Man United Vs Chelsea showdown in the EPL today:
Man Utd XI: De Gea, Dalot, Smalling, Lindelof, Shaw, Fred, Pogba, Matic, Lingard, Rashford, Martial
Chelsea XI: Kepa, Azpilicueta, Rudiger, Luiz, Emerson, Jorginho, Kovacic, Barkley, Hazard, Higuain, Willian
Provisional Man Utd squad: De Gea, Romero, Grant, Dalot, Darmian, Bailly, Valencia, Young, Jones, Shaw, Lindelof, Rojo, Smalling, Herrera, Fred, Matic, McTominay, Pereira, Pogba, Lingard, Mata, Martial, Sanchez, Lukaku, Rashford
Provisional Chelsea squad: Kepa, Azpilicueta, Emerson, Rudiger, Christensen, Luiz, Jorginho, Kante, Loftus-Cheek, Higuain, Hazard, Willian, Pedro, Barkley, Caballero, Barkley, Kovacic, Giroud, Alonso, Cahill