The first leg of the clash at the White Hart Lane ended 1-0 in Spurs’ favour meaning the tie finished 4-4 on aggregate.
However, it was the London side that advanced to the semi-final of the competition on the away goals rule.
Raheem Sterling netted a brace with Bernado Silva and Sergio Aguero scoring one goal each for City.
On the other hand, Son Heung-min scored two goals with Fernando Llorente getting one for Maurizio Pochettino’s men during the encounter at the Etihad Stadium.
In the other game, Liverpool massacred Porto 4-1 to advance to the next stage of the competition on a 1-6 aggregate win.