Despite some injury worries, Pep Guardiola will still have close to a strong squad available for against Chelsea, but it could difficult predicting who the manager start for the crunch encounter.
De Bruyne missed out in midweek but that was a fitness/rotation issue rather than injury.
Benjamin Mendy, however, has not featured in the last three Premier League games despite playing 27 minutes in the Carabao Cup on January 23.
Vincent Kompany is still out, as is Claudio Bravo.
This one could be anything. Perhaps Guardiola will use Fernandinho as a centre-back/midfielder again or perhaps that was uniquely applicable to Arsenal.
Bernardo Silva seems to start every game at the moment and there is likely to be space for him again, while De Bruyne is also a good bet to play.
Guardiola only picked one of Raheem Sterling and Leroy Sane alongside Sergio Aguero in the past two games but could use more of a traditional front three with two wingers on Sunday. That could also see Gabriel Jesus come in for Aguero.
The Blues followed up a heavy defeat with a big win, but they now face the Premier League champions, who are at the heart of another title race.
However, Chelsea is in good shape ahead of their trip to Manchester and had only left out Antonio Rudiger for last week’s victory against bottom-of-the-table Huddersfield.
Sarri’s team selections have been broadly predictable otherwise, as they line up in a 4-3-3, with N’Golo Kante, Cesar Azpilicueta and Kepa Arrizabalaga having started every league match. Alonso, Jorginho and Rudiger have started all but one of their side’s league games.
Kick off is 16:00 GMT (11 ET) on Sunday, and will be shown on Sky Sports in the United Kingdom. It will be shown on NBC in the United States, and on various channels around the world.