Super Eagles captain Mikel John Obi will be out for the rest of the season after he suffered a muscle injury in training.
Mikel did not feature in full training for Tianjin Teda in the China Super League on Tuesday as he only jogged on the sidelines.
The development is a major blow for coach Uli Stielike, whose side need the experience of the former Chelsea man to get their first win after 11 games.
Mikel has played 18 league games this term and has scored two goals in the process.
He has not played for Nigeria since the team crashed out of the 2018 World Cup in Russia.