Jamie Vardy and Gary Cahill have called time on their careers with England to allow manager Gareth Southgate to bring in younger players.
They however said they were “not shutting the door completely.”
“This has been on my mind for a while,” Vardy told told the Guardian UK.
“I’m not getting any younger and you can see, to be fair to the gaffer, he wants to make it more youthful, which obviously had its benefits during the World Cup.”
The Leicester City striker won 26 international caps.
And on his part, Cahill, 32, scored five goals in 61 games for England.
He made his debut in 2010, and captained the side on several occasions.
“I can see it is now going to a younger generation and I think it is the perfect time for me to take a step back,” Cahill told Chelsea TV.
“I’ve been hugely honoured to play for my country and I would never shut the door.
“I’ve said that if there are injuries in the future and I’m needed to come and play then, of course, I’m available.”